RAB26 Antibody (PACO56242)
- SKU:
- PACO56242
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RAB26 Antibody (PACO56242) |
抗体コード: | PACO56242 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
反応性: | Human, Rat |
免疫原: | Recombinant Human Ras-related protein Rab-26 protein (1-58AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Rat liver tissue. All lanes: RAB26 antibody at 5.9µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 28, 22 kDa. Observed band size: 28 kDa. |
![]() | IHC image of PACO56242 diluted at 1:200 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | IHC image of PACO56242 diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland. |
シノニム: | Ras-related protein Rab-26, RAB26 |
UniProt Protein Function: | RAB26: Participates in exocrine secretion: regulates the secretion of acinar granules in the parotid gland. Belongs to the small GTPase superfamily. Rab family. |
UniProt Protein Details: | Protein type:G protein, monomeric, Rab; G protein, monomeric; G protein Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: Golgi membrane; intrinsic to plasma membrane; secretory granule membrane Molecular Function:GMP binding; GTP binding; protein binding Biological Process: exocrine system development; Golgi to plasma membrane protein transport; regulated secretory pathway; regulation of exocytosis |
NCBI Summary: | Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010] |
UniProt Code: | Q9ULW5 |
NCBI GenInfo Identifier: | 134044256 |
NCBI Gene ID: | 25837 |
NCBI Accession: | Q9ULW5.3 |
UniProt Secondary Accession: | Q9ULW5,Q3L6K5, Q6NXS7, B2RAA6, |
UniProt Related Accession: | Q9ULW5 |
Molecular Weight: | 21,355 Da |
NCBI Full Name: | Ras-related protein Rab-26 |
NCBI Synonym Full Names: | RAB26, member RAS oncogene family |
NCBI Official Symbol: | RAB26 |
NCBI Official Synonym Symbols: | V46133 |
NCBI Protein Information: | ras-related protein Rab-26 |
UniProt Protein Name: | Ras-related protein Rab-26 |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAB26 |
UniProt Entry Name: | RAB26_HUMAN |