RAB18 Antibody (PACO45573)
- SKU:
- PACO45573
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RAB18 Antibody (PACO45573) |
抗体コード: | PACO45573 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Ras-related protein Rab-18 protein (1-206AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: RAB18 antibody at 0.88µg/ml. Lane 1: HepG2 whole cell lysate. Lane 2: PC-3 whole cell lysate. Lane 3: A375 whole cell lysate. Lane 4: 293T whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 23, 27, 16 kDa. Observed band size: 23 kDa.. | |
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO45573 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human liver cancer using PACO45573 at dilution of 1:100. |
バックグラウンド: | Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration. |
シノニム: | Ras-related protein Rab-18, RAB18 |
UniProt Protein Function: | RAB18: a small G protein that plays a role in apical endocytosis/recycling. May be involved in transport between the plasma membrane and early endosomes. |
UniProt Protein Details: | Protein type:G protein; G protein, monomeric, Rab; G protein, monomeric Chromosomal Location of Human Ortholog: 10p12.1 Cellular Component: Golgi apparatus; plasma membrane; intracellular Molecular Function:GTPase activity; protein binding; GDP binding; GTP binding Biological Process: intracellular protein transport; eye development; metabolic process; small GTPase mediated signal transduction; brain development; Rab protein signal transduction Disease: Warburg Micro Syndrome 3 |
NCBI Summary: | The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] |
UniProt Code: | Q9NP72 |
NCBI GenInfo Identifier: | 12230528 |
NCBI Gene ID: | 22931 |
NCBI Accession: | Q9NP72.1 |
UniProt Secondary Accession: | Q9NP72,Q53FX8, Q56UN9, Q6FIH1, B3KMC7, B7Z333, D3DRW1 |
UniProt Related Accession: | Q9NP72 |
Molecular Weight: | 206 |
NCBI Full Name: | Ras-related protein Rab-18 |
NCBI Synonym Full Names: | RAB18, member RAS oncogene family |
NCBI Official Symbol: | RAB18 |
NCBI Official Synonym Symbols: | WARBM3; RAB18LI1 |
NCBI Protein Information: | ras-related protein Rab-18; RAB18 small GTPase |
UniProt Protein Name: | Ras-related protein Rab-18 |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAB18 |
UniProt Entry Name: | RAB18_HUMAN |