PURA Antibody, FITC conjugated (PACO57938)
- SKU:
- PACO57938
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | PURA Antibody, FITC conjugated (PACO57938) |
抗体コード: | PACO57938 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Transcriptional activator protein Pur-α protein (50-296AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination. |
シノニム: | Transcriptional activator protein Pur-α (Purine-rich single-stranded DNA-binding protein alpha), PURA, PUR1 |
UniProt Protein Function: | PURA: This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination. Belongs to the PUR DNA-binding protein family. |
UniProt Protein Details: | Protein type:DNA-binding; RNA-binding Chromosomal Location of Human Ortholog: 5q31 Cellular Component: DNA replication factor A complex; nuclear chromosome, telomeric region; nucleus Molecular Function:double-stranded telomeric DNA binding; protein binding; RNA polymerase II transcription factor activity, enhancer binding; single-stranded DNA binding; transcription factor binding Biological Process: DNA replication initiation; DNA unwinding during replication Disease: Mental Retardation, Autosomal Dominant 31 |
NCBI Summary: | This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q00577 |
NCBI GenInfo Identifier: | 1346918 |
NCBI Gene ID: | 5813 |
NCBI Accession: | Q00577.2 |
UniProt Related Accession: | Q00577 |
Molecular Weight: | 34,911 Da |
NCBI Full Name: | Transcriptional activator protein Pur-alpha |
NCBI Synonym Full Names: | purine rich element binding protein A |
NCBI Official Symbol: | PURA |
NCBI Official Synonym Symbols: | PUR1; MRD31; PURALPHA; PUR-ALPHA |
NCBI Protein Information: | transcriptional activator protein Pur-alpha |
UniProt Protein Name: | Transcriptional activator protein Pur-alpha |
UniProt Synonym Protein Names: | Purine-rich single-stranded DNA-binding protein alpha |
Protein Family: | Puratrophin |
UniProt Gene Name: | PURA |
UniProt Entry Name: | PURA_HUMAN |