PTPRS Antibody, HRP conjugated (PACO46483)
- SKU:
- PACO46483
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | PTPRS Antibody, HRP conjugated (PACO46483) |
抗体コード: | PACO46483 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Receptor-type tyrosine-protein phosphatase S protein (25-128AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Interacts with LAR-interacting protein LIP.1. |
シノニム: | Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma), PTPRS |
UniProt Protein Function: | PTPRS: Interacts with LAR-interacting protein LIP.1. Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily. 7 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; EC 3.1.3.48; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: integral to plasma membrane Molecular Function:protein binding; transmembrane receptor protein tyrosine phosphatase activity Biological Process: corpus callosum development; extracellular matrix organization and biogenesis; spinal cord development; hippocampus development; cerebellum development; cerebral cortex development; cell adhesion |
NCBI Summary: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q13332 |
NCBI GenInfo Identifier: | 119589584 |
NCBI Gene ID: | 5802 |
NCBI Accession: | EAW69178.1 |
UniProt Secondary Accession: | Q13332,O75255, O75870, Q15718, Q16341, Q2M3R7, |
UniProt Related Accession: | Q13332 |
Molecular Weight: | |
NCBI Full Name: | protein tyrosine phosphatase, receptor type, S, isoform CRA_h |
NCBI Synonym Full Names: | protein tyrosine phosphatase, receptor type, S |
NCBI Official Symbol: | PTPRS |
NCBI Official Synonym Symbols: | PTPSIGMA |
NCBI Protein Information: | receptor-type tyrosine-protein phosphatase S; R-PTP-S; R-PTP-sigma; protein tyrosine phosphatase PTPsigma; receptor-type tyrosine-protein phosphatase sigma; protein tyrosine phosphatase, receptor type, sigma |
UniProt Protein Name: | Receptor-type tyrosine-protein phosphatase S |
UniProt Synonym Protein Names: | Receptor-type tyrosine-protein phosphatase sigma |
Protein Family: | Receptor-type tyrosine-protein phosphatase |
UniProt Gene Name: | PTPRS |
UniProt Entry Name: | PTPRS_HUMAN |