PTPN3 Antibody, FITC conjugated (PACO57934)
- SKU:
- PACO57934
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | PTPN3 Antibody, FITC conjugated (PACO57934) |
抗体コード: | PACO57934 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Tyrosine-protein phosphatase non-receptor type 3 protein (365-505AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity. |
シノニム: | Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1), PTPN3, PTPH1 |
UniProt Protein Function: | PTPN3: May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. |
UniProt Protein Details: | Protein type:EC 3.1.3.48; Motility/polarity/chemotaxis; Protein phosphatase, tyrosine (non-receptor) Chromosomal Location of Human Ortholog: 9q31 Cellular Component: internal side of plasma membrane; cytoskeleton; cytoplasm Molecular Function:protein binding; sodium channel regulator activity; phosphotyrosine binding; cytoskeletal protein binding; protein tyrosine phosphatase activity; ATPase binding Biological Process: negative regulation of mitotic cell cycle; protein amino acid dephosphorylation; negative regulation of membrane protein ectodomain proteolysis |
NCBI Summary: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009] |
UniProt Code: | P26045 |
NCBI GenInfo Identifier: | 229462761 |
NCBI Gene ID: | 5774 |
NCBI Accession: | P26045.2 |
UniProt Secondary Accession: | P26045,A0AUW9, E7EN99, E9PGU7, |
UniProt Related Accession: | P26045 |
Molecular Weight: | 913 |
NCBI Full Name: | Tyrosine-protein phosphatase non-receptor type 3 |
NCBI Synonym Full Names: | protein tyrosine phosphatase, non-receptor type 3 |
NCBI Official Symbol: | PTPN3 |
NCBI Official Synonym Symbols: | PTPH1; PTP-H1 |
NCBI Protein Information: | tyrosine-protein phosphatase non-receptor type 3; protein-tyrosine phosphatase H1; cytoskeletal-associated protein tyrosine phosphatase |
UniProt Protein Name: | Tyrosine-protein phosphatase non-receptor type 3 |
UniProt Synonym Protein Names: | Protein-tyrosine phosphatase H1; PTP-H1 |
Protein Family: | Tyrosine-protein phosphatase non-receptor |
UniProt Gene Name: | PTPN3 |
UniProt Entry Name: | PTN3_HUMAN |