PTK7 Antibody (PACO61971)
- SKU:
- PACO61971
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PTK7 Antibody (PACO61971) |
抗体コード: | PACO61971 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Inactive tyrosine-protein kinase 7 protein (772-1070AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO61971 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. |
シノニム: | Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7), PTK7, CCK4 |
UniProt Protein Function: | Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. |
NCBI Summary: | This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
UniProt Code: | Q13308 |
NCBI GenInfo Identifier: | 116242736 |
NCBI Gene ID: | 5754 |
NCBI Accession: | Q13308.2 |
UniProt Secondary Accession: | Q13308,Q13417, Q5T650, Q6IQ54, Q8NFA5, Q8NFA6, Q8NFA7 Q8NFA8, A8K974, B7Z477, E9PFZ5, |
UniProt Related Accession: | Q13308 |
Molecular Weight: | 119,197 Da |
NCBI Full Name: | Inactive tyrosine-protein kinase 7 |
NCBI Synonym Full Names: | protein tyrosine kinase 7 (inactive) |
NCBI Official Symbol: | PTK7 |
NCBI Official Synonym Symbols: | CCK4; CCK-4 |
NCBI Protein Information: | inactive tyrosine-protein kinase 7 |
UniProt Protein Name: | Inactive tyrosine-protein kinase 7 |
UniProt Synonym Protein Names: | Colon carcinoma kinase 4; CCK-4; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Tyrosine-protein kinase-like 7 |
Protein Family: | Inactive tyrosine-protein kinase |
UniProt Gene Name: | PTK7 |
UniProt Entry Name: | PTK7_HUMAN |
Antibodies |
Anti-PTK7 Antibody (CAB9839) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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