PTH Antibody (PACO21657)
- SKU:
- PACO21657
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | PTH Antibody (PACO21657) |
抗体コード: | PACO21657 |
サイズ: | 100ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
反応性: | Human |
免疫原: | Synthesized peptide derived from human Parathyroid Hormone antibody. |
憲法: | Liquid |
ストレージバッファ: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from A549 cells, using Parathyroid Hormone antibody. |
バックグラウンド: | PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. |
シノニム: | PTH/PTHr receptor; PTH/PTHrP type I receptor; PTHR1; Parathyroid hormone/parathyroid hormone-related peptide receptor precursor; |
UniProt Protein Function: | PTH: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. Belongs to the parathyroid hormone family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Hormone; Apoptosis Chromosomal Location of Human Ortholog: 11p15.3-p15.1 Cellular Component: extracellular space; extracellular region Molecular Function:RNA polymerase II transcription factor activity, enhancer binding; type 1 parathyroid hormone receptor binding; parathyroid hormone receptor binding; peptide hormone receptor binding; hormone activity Biological Process: response to drug; transcription from RNA polymerase II promoter; positive regulation of signal transduction; induction of apoptosis by hormones; positive regulation of glycogen biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of bone mineralization; G-protein signaling, adenylate cyclase activating pathway; Rho protein signal transduction; cellular calcium ion homeostasis; positive regulation of glucose import; G-protein coupled receptor protein signaling pathway; cAMP metabolic process; response to vitamin D; response to cadmium ion; response to ethanol; cell-cell signaling; regulation of gene expression; positive regulation of cAMP biosynthetic process; response to lead ion; positive regulation of transcription from RNA polymerase II promoter; skeletal development; bone resorption Disease: Hypoparathyroidism, Familial Isolated |
NCBI Summary: | The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH). [provided by RefSeq, Jul 2008] |
UniProt Code: | P01270 |
NCBI GenInfo Identifier: | 131547 |
NCBI Gene ID: | 5741 |
NCBI Accession: | P01270.1 |
UniProt Secondary Accession: | P01270,Q4VB48, Q9UD38, |
UniProt Related Accession: | P01270 |
Molecular Weight: | 12,861 Da |
NCBI Full Name: | Parathyroid hormone |
NCBI Synonym Full Names: | parathyroid hormone |
NCBI Official Symbol: | PTH |
NCBI Official Synonym Symbols: | PTH1 |
NCBI Protein Information: | parathyroid hormone; parathyrin; prepro-PTH; parathormone; parathyroid hormone 1; preproparathyroid hormone |
UniProt Protein Name: | Parathyroid hormone |
UniProt Synonym Protein Names: | Parathormone; Parathyrin |
Protein Family: | Parathyroid hormone |
UniProt Gene Name: | PTH |
UniProt Entry Name: | PTHY_HUMAN |
Antibodies | ELISA Kits |
Anti-PTH Antibody (CAB5846) | Human PTH ELISA Kit |
PTH Antibody (PACO01375) | Human Parathyroid hormone (PTH) ELISA Kit |
Parathyroid Hormone Colorimetric Cell-Based ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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