PTGES2 Antibody (PACO14943)
- SKU:
- PACO14943
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PTGES2 Antibody (PACO14943) |
抗体コード: | PACO14943 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
反応性: | Human, Mouse |
免疫原: | Fusion protein of human PTGES2 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela cells, A549 cells, lncap cells, Primary antibody: PACO14943(PTGES2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
バックグラウンド: | Prostaglandin E synthase 2 is an enzyme that in humans is encoded by the PTGES2 gene. The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. |
シノニム: | Prostaglandin E synthase 2 |
UniProt Protein Function: | PTGES2: Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. Belongs to the GST superfamily. |
UniProt Protein Details: | Protein type:Isomerase; EC 5.3.99.3; Lipid Metabolism - arachidonic acid; Membrane protein, integral Chromosomal Location of Human Ortholog: 9q34.11 Cellular Component: Golgi membrane; mitochondrion; perinuclear region of cytoplasm; integral to membrane; cytosol; nucleus Molecular Function:DNA binding; glutathione binding; electron carrier activity; lyase activity; heme binding; protein disulfide oxidoreductase activity; prostaglandin-E synthase activity Biological Process: secretion; cell redox homeostasis; positive regulation of transcription, DNA-dependent; prostaglandin biosynthetic process |
NCBI Summary: | The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009] |
UniProt Code: | Q9H7Z7 |
NCBI GenInfo Identifier: | 73921741 |
NCBI Gene ID: | 80142 |
NCBI Accession: | Q9H7Z7.1 |
UniProt Secondary Accession: | Q9H7Z7,Q53EW9, Q5SYV6, Q96GI0, Q96GL2, |
UniProt Related Accession: | Q9H7Z7 |
Molecular Weight: | |
NCBI Full Name: | Prostaglandin E synthase 2 |
NCBI Synonym Full Names: | prostaglandin E synthase 2 |
NCBI Official Symbol: | PTGES2 |
NCBI Official Synonym Symbols: | GBF1; GBF-1; PGES2; C9orf15; mPGES-2 |
NCBI Protein Information: | prostaglandin E synthase 2; GATE-binding factor 1; gamma-interferon-activated transcriptional element-binding factor 1; mPGE synthase-2; membrane-associated prostaglandin E synthase 2; membrane-associated prostaglandin E synthase-2; microsomal prostaglandin E synthase-2; prostaglandin-H(2) E-isomerase |
UniProt Protein Name: | Prostaglandin E synthase 2 |
UniProt Synonym Protein Names: | Membrane-associated prostaglandin E synthase-2 |
UniProt Gene Name: | PTGES2 |
UniProt Entry Name: | PGES2_HUMAN |