PSMD6 Antibody, HRP conjugated (PACO62044)
- SKU:
- PACO62044
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Description
抗体名: | PSMD6 Antibody, HRP conjugated (PACO62044) |
抗体コード: | PACO62044 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Peptide sequence from Human 26S proteasome non-ATPase regulatory subunit 6 protein (355-372AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. |
シノニム: | 26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A), PSMD6, KIAA0107 PFAAP4 |
UniProt Protein Function: | PSMD6: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Belongs to the proteasome subunit S10 family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3p14.1 Cellular Component: nucleoplasm; proteasome complex; proteasome regulatory particle; cytosol Molecular Function:ATPase activity Biological Process: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; protein polyubiquitination; viral reproduction; apoptosis; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; proteolysis; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of apoptosis; antigen processing and presentation of peptide antigen via MHC class I; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; gene expression; mitotic cell cycle; regulation of amino acid metabolic process; negative regulation of apoptosis; G1/S transition of mitotic cell cycle |
NCBI Summary: | This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012] |
UniProt Code: | Q15008 |
NCBI GenInfo Identifier: | 7661914 |
NCBI Gene ID: | 9861 |
NCBI Accession: | NP_055629.1 |
UniProt Secondary Accession: | Q15008,Q6UV22, A8K2E0, E9PHI9, |
UniProt Related Accession: | Q15008 |
Molecular Weight: | 51,923 Da |
NCBI Full Name: | 26S proteasome non-ATPase regulatory subunit 6 isoform 2 |
NCBI Synonym Full Names: | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 |
NCBI Official Symbol: | PSMD6 |
NCBI Official Synonym Symbols: | S10; Rpn7; p42A; p44S10; SGA-113M |
NCBI Protein Information: | 26S proteasome non-ATPase regulatory subunit 6; breast cancer-associated protein SGA-113M; phosphonoformate immuno-associated protein 4; proteasome regulatory particle subunit p44S10 |
UniProt Protein Name: | 26S proteasome non-ATPase regulatory subunit 6 |
UniProt Synonym Protein Names: | 26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; Phosphonoformate immuno-associated protein 4; Proteasome regulatory particle subunit p44S10; p42A |
UniProt Gene Name: | PSMD6 |
UniProt Entry Name: | PSMD6_HUMAN |