PPME1 Antibody (PACO29120)
- SKU:
- PACO29120
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PPME1 Antibody (PACO29120) |
抗体コード: | PACO29120 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Protein phosphatase methylesterase 1 protein (201-386AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: PPME1 antibody at 2µg/ml Lane 1: A549 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: Mouse brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 43, 23, 19, 44 kDa Observed band size: 43 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human liver cancer using PACO29120 at dilution of 1:100. |
バックグラウンド: | Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme. |
シノニム: | Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89), PPME1, PME1 |
UniProt Protein Function: | PPME1: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme. Belongs to the AB hydrolase superfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Hydrolase; Motility/polarity/chemotaxis; EC 3.1.1.89; Protein phosphatase, regulatory subunit Chromosomal Location of Human Ortholog: 11q13.4 Molecular Function:protein C-terminal methylesterase activity; protein phosphatase 2A binding; protein phosphatase binding; protein phosphatase inhibitor activity; protein phosphatase type 2A regulator activity Biological Process: protein amino acid demethylation |
NCBI Summary: | This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012] |
UniProt Code: | Q9Y570 |
NCBI GenInfo Identifier: | 47606055 |
NCBI Gene ID: | 51400 |
NCBI Accession: | Q9Y570.3 |
UniProt Secondary Accession: | Q9Y570,Q8WYG8, Q9NVT5, Q9UI18, B3KMU6, B5MEE7, J3QT22 |
UniProt Related Accession: | Q9Y570 |
Molecular Weight: | 43,870 Da |
NCBI Full Name: | Protein phosphatase methylesterase 1 |
NCBI Synonym Full Names: | protein phosphatase methylesterase 1 |
NCBI Official Symbol: | PPME1 |
NCBI Official Synonym Symbols: | PME-1 |
NCBI Protein Information: | protein phosphatase methylesterase 1 |
UniProt Protein Name: | Protein phosphatase methylesterase 1 |
Protein Family: | Pectinesterase |
UniProt Gene Name: | PPME1 |
UniProt Entry Name: | PPME1_HUMAN |
Antibodies | ELISA Kits |
Anti-PPME1 Antibody (CAB13094) | Human Protein phosphatase methylesterase 1 (PPME1) ELISA Kit |
PPME1 Antibody (PACO11414) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |