PLXNA1 Antibody (PACO33428)
- SKU:
- PACO33428
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PLXNA1 Antibody (PACO33428) |
抗体コード: | PACO33428 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:10-1:100 |
反応性: | Human |
免疫原: | Recombinant Human Plexin-A1 protein (32-296AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO33428 at dilution of 1:20. |
バックグラウンド: | Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm |
シノニム: | Plexin-A1 (Semaphorin receptor NOV), PLXNA1, NOV PLXN1 |
UniProt Protein Function: | PLXNA1: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm. Interacts directly with NRP1 and NRP2. Interacts with FARP2, RND1 and KDR/VEGFR2. Binding of SEMA3A leads to dissociation of FARP2. Detected in fetal brain, lung, liver and kidney. Belongs to the plexin family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q21.3 Cellular Component: cytoplasm; integral to membrane; plasma membrane; nucleus Molecular Function:semaphorin receptor activity; receptor activity Biological Process: axon guidance; regulation of smooth muscle cell migration; multicellular organismal development |
UniProt Code: | Q9UIW2 |
NCBI GenInfo Identifier: | 313104202 |
NCBI Gene ID: | 5361 |
NCBI Accession: | Q9UIW2.3 |
UniProt Related Accession: | Q9UIW2 |
Molecular Weight: | 211,067 Da |
NCBI Full Name: | Plexin-A1 |
NCBI Synonym Full Names: | plexin A1 |
NCBI Official Symbol: | PLXNA1 |
NCBI Official Synonym Symbols: | NOV; NOVP; PLXN1; PLEXIN-A1 |
NCBI Protein Information: | plexin-A1; plexin 1; semaphorin receptor NOV |
UniProt Protein Name: | Plexin-A1 |
UniProt Synonym Protein Names: | Semaphorin receptor NOV |
Protein Family: | Plexin |
UniProt Gene Name: | PLXNA1 |
UniProt Entry Name: | PLXA1_HUMAN |
Antibodies |
Anti-PLXNA1 Antibody (CAB18264) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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