PLXNA1 Antibody (PACO20244)
- SKU:
- PACO20244
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PLXNA1 Antibody (PACO20244) |
抗体コード: | PACO20244 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Synthetic peptide of human PLXNA1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20244(PLXNA1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO20244(PLXNA1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Plexins are a family of large, transmembrane receptors for multiple classes of semaphorins in vertebrates. Plexins are widely expressed, and regions of their extracellular domain are homologus to both scatter factor receptors and semaphorin domains. |
シノニム: | plexin A1 |
UniProt Protein Function: | PLXNA1: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm. Interacts directly with NRP1 and NRP2. Interacts with FARP2, RND1 and KDR/VEGFR2. Binding of SEMA3A leads to dissociation of FARP2. Detected in fetal brain, lung, liver and kidney. Belongs to the plexin family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q21.3 Cellular Component: cytoplasm; integral to membrane; plasma membrane; nucleus Molecular Function:semaphorin receptor activity; receptor activity Biological Process: axon guidance; regulation of smooth muscle cell migration; multicellular organismal development |
UniProt Code: | Q9UIW2 |
NCBI GenInfo Identifier: | 313104202 |
NCBI Gene ID: | 5361 |
NCBI Accession: | Q9UIW2.3 |
UniProt Related Accession: | Q9UIW2 |
Molecular Weight: | 211,067 Da |
NCBI Full Name: | Plexin-A1 |
NCBI Synonym Full Names: | plexin A1 |
NCBI Official Symbol: | PLXNA1 |
NCBI Official Synonym Symbols: | NOV; NOVP; PLXN1; PLEXIN-A1 |
NCBI Protein Information: | plexin-A1; plexin 1; semaphorin receptor NOV |
UniProt Protein Name: | Plexin-A1 |
UniProt Synonym Protein Names: | Semaphorin receptor NOV |
Protein Family: | Plexin |
UniProt Gene Name: | PLXNA1 |
UniProt Entry Name: | PLXA1_HUMAN |
Antibodies |
Anti-PLXNA1 Antibody (CAB18264) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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