Plaur Antibody, Biotin conjugated (PACO28989)
- SKU:
- PACO28989
- Product type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | Plaur Antibody, Biotin conjugated (PACO28989) |
抗体コード: | PACO28989 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Rat |
免疫原: | Recombinant Rat Urokinase plasminogen activator surface receptor ptotein (25-299AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. |
シノニム: | Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (CD_antigen: CD87), Plaur |
UniProt Protein Function: | uPAR: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. Monomer (Probable). Interacts with MRC2. Interacts (via the UPAR/Ly6 domains) with SRPX2. Expressed in neurons of the rolandic area of the brain. Expressed in the brain. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, GPI anchor; Motility/polarity/chemotaxis; Receptor, misc. Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cell surface; extracellular region; focal adhesion; integral component of plasma membrane; plasma membrane Molecular Function:enzyme binding; protein domain specific binding; receptor binding; U-plasminogen activator receptor activity Biological Process: mesenchymal cell differentiation; negative regulation of apoptosis; positive regulation of DNA binding; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of protein phosphorylation; regulation of proteolysis; skeletal muscle tissue regeneration; spermatogenesis |
NCBI Summary: | receptor for urokinase-plasminogen activator; may play a central role in malignant tumour progression [RGD, Feb 2006] |
UniProt Code: | P49616 |
NCBI GenInfo Identifier: | 8394516 |
NCBI Gene ID: | 50692 |
NCBI Accession: | NP_059046.1 |
UniProt Secondary Accession: | P49616,O35771, P51573, Q7TN35, |
UniProt Related Accession: | P49616 |
Molecular Weight: | 24,417 Da |
NCBI Full Name: | urokinase plasminogen activator surface receptor isoform 2 |
NCBI Synonym Full Names: | plasminogen activator, urokinase receptor |
NCBI Official Symbol: | Plaur |
NCBI Official Synonym Symbols: | Par; uPAR; Plaur3; uPAR-2; uPAR-3 |
NCBI Protein Information: | urokinase plasminogen activator surface receptor |
UniProt Protein Name: | Urokinase plasminogen activator surface receptor |
UniProt Synonym Protein Names: | CD_antigen: CD87 |
UniProt Gene Name: | Plaur |