PITX2 Antibody (PACO50978)
- SKU:
- PACO50978
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PITX2 Antibody (PACO50978) |
抗体コード: | PACO50978 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Pituitary homeobox 2 protein (40-154AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate. All lanes: PITX2 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 36, 31 kDa. Observed band size: 42 kDa.. | |
Immunohistochemistry of paraffin-embedded human duodenum tissue using PACO50978 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO50978 at dilution of 1:100. |
バックグラウンド: | Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo (By similarity). |
シノニム: | Pituitary homeobox 2 (ALL1-responsive protein ARP1) (Homeobox protein PITX2) (Paired-like homeodomain transcription factor 2) (RIEG bicoid-related homeobox transcription factor) (Solurshin), PITX2, ARP1 RGS RIEG RIEG1 |
UniProt Protein Function: | Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo. |
NCBI Summary: | This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99697 |
NCBI GenInfo Identifier: | 6174907 |
NCBI Gene ID: | 5308 |
NCBI Accession: | Q99697.2 |
UniProt Secondary Accession: | Q99697,O60578, O60579, O60580, Q3KQX9, Q9BY17, A8K6C6 B2RA02, B3KXS0, |
UniProt Related Accession: | Q99697 |
Molecular Weight: | 30,336 Da |
NCBI Full Name: | Pituitary homeobox 2 |
NCBI Synonym Full Names: | paired like homeodomain 2 |
NCBI Official Symbol: | PITX2 |
NCBI Official Synonym Symbols: | RS; RGS; ARP1; Brx1; IDG2; IGDS; IHG2; PTX2; RIEG; IGDS2; IRID2; Otlx2; RIEG1 |
NCBI Protein Information: | pituitary homeobox 2 |
UniProt Protein Name: | Pituitary homeobox 2 |
UniProt Synonym Protein Names: | ALL1-responsive protein ARP1; Homeobox protein PITX2; Paired-like homeodomain transcription factor 2; RIEG bicoid-related homeobox transcription factor; Solurshin |
Protein Family: | Pituitary homeobox |
UniProt Gene Name: | PITX2 |
UniProt Entry Name: | PITX2_HUMAN |
Antibodies | ELISA Kits |
Anti-PITX2 Antibody (CAB16417) | Human PITX2 (Pituitary homeobox 2) ELISA Kit (HUFI07195) |
Anti-PITX2 Antibody (CAB1870) | |
PITX2 Antibody (PACO11265) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |