PITRM1 Antibody (PACO11263)
- SKU:
- PACO11263
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PITRM1 Antibody (PACO11263) |
抗体コード: | PACO11263 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human PITRM1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | pitrilysin metallopeptidase 1;PITRM1;KIAA1104;MGC138192;MGC141929;MP1;PreP;hMP1 ; |
UniProt Protein Function: | PITRM1: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. Belongs to the peptidase M16 family. PreP subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Mitochondrial; Protease; EC 3.4.24.-; Activator Chromosomal Location of Human Ortholog: 10p15.2 Cellular Component: mitochondrial matrix; mitochondrion Molecular Function:enzyme activator activity; metalloendopeptidase activity; zinc ion binding Biological Process: protein processing; proteolysis |
UniProt Code: | Q5JRX3 |
NCBI GenInfo Identifier: | 485956568 |
NCBI Gene ID: | 10531 |
NCBI Accession: | Q5JRX3.3 |
UniProt Secondary Accession: | Q5JRX3,O95204, Q2M2G6, Q4VBR1, Q5JRW7, Q7L5Z7, Q9BSI6 Q9BVJ5, B3KMJ6, B4E0J8, C9JSL2, E7ES23, |
UniProt Related Accession: | Q5JRX3 |
Molecular Weight: | 106,065 Da |
NCBI Full Name: | Presequence protease, mitochondrial |
NCBI Synonym Full Names: | pitrilysin metallopeptidase 1 |
NCBI Official Symbol: | PITRM1 |
NCBI Official Synonym Symbols: | MP1; PreP |
NCBI Protein Information: | presequence protease, mitochondrial |
UniProt Protein Name: | Presequence protease, mitochondrial |
UniProt Synonym Protein Names: | Pitrilysin metalloproteinase 1; Metalloprotease 1; hMP1 |
UniProt Gene Name: | PITRM1 |
UniProt Entry Name: | PREP_HUMAN |