PIP4K2B Antibody (PACO43534)
- SKU:
- PACO43534
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PIP4K2B Antibody (PACO43534) |
抗体コード: | PACO43534 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Phosphatidylinositol 5-phosphate 4-kinase type-2 β protein (1-270AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: Phosphatidylinositol 5-phosphate 4-kinase type-2 beta antibody at 10µg/ml. Lane 1: Hela whole cell lysate. Lane 2: MCF-7 whole cell lysate. Lane 3: 293T whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 48, 33 kDa. Observed band size: 48 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO43534 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human breast cancer using PACO43534 at dilution of 1:100. |
バックグラウンド: | Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. |
シノニム: | Phosphatidylinositol 5-phosphate 4-kinase type-2 β (EC 2.7.1.149) (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-beta) (PtdIns(5)P-4-kinase isoform 2-beta), PIP4K2B, PIP5K2B |
UniProt Protein Function: | PIP4K2B: Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Homodimer. Binds TNFRSF1A. Interacts with PIP4K2A. Interaction with PIP4K2A suppresses ubiquitination by the SPOP/ CUL3 complex. Highly expressed in brain, heart, pancreas, skeletal muscle and kidney. Detected at lower levels in placenta, lung and liver. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.149; Kinase, lipid; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 17q12 Cellular Component: autophagic vacuole; cytosol; nucleoplasm Molecular Function:1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-phosphate 4-kinase activity; protein binding; protein homodimerization activity; receptor signaling protein activity Biological Process: cell surface receptor linked signal transduction; phosphatidylinositol biosynthetic process; phospholipid metabolic process; regulation of autophagy; regulation of phosphoinositide 3-kinase cascade |
NCBI Summary: | The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008] |
UniProt Code: | P78356 |
NCBI GenInfo Identifier: | 47605991 |
NCBI Gene ID: | 8396 |
NCBI Accession: | P78356.1 |
UniProt Secondary Accession: | P78356,Q5U0E8, Q8TBP2, |
UniProt Related Accession: | P78356 |
Molecular Weight: | Calculated MW: 32kDa/47kDaObserved MW: 47kDa |
NCBI Full Name: | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta |
NCBI Synonym Full Names: | phosphatidylinositol-5-phosphate 4-kinase type 2 beta |
NCBI Official Symbol: | PIP4K2B |
NCBI Official Synonym Symbols: | PI5P4KB; PIP5K2B; PIP5KIIB; PIP5P4KB; PIP5KIIbeta |
NCBI Protein Information: | phosphatidylinositol 5-phosphate 4-kinase type-2 beta |
UniProt Protein Name: | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta |
UniProt Synonym Protein Names: | 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; Diphosphoinositide kinase 2-beta; Phosphatidylinositol 5-phosphate 4-kinase type II beta; PI(5)P 4-kinase type II beta; PIP4KII-beta; PtdIns(5)P-4-kinase isoform 2-beta |
Protein Family: | Phosphatidylinositol 5-phosphate 4-kinase |
UniProt Gene Name: | PIP4K2B |