PIGW Antibody, FITC conjugated (PACO58242)
- SKU:
- PACO58242
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | PIGW Antibody, FITC conjugated (PACO58242) |
抗体コード: | PACO58242 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Phosphatidylinositol-glycan biosynthesis class W protein (392-448AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity). |
シノニム: | Phosphatidylinositol-glycan biosynthesis class W protein (PIG-W) (EC 2.3), PIGW |
UniProt Protein Function: | Required for the transport of GPI-anchored proteins to the plasma membrane (PubMed:24367057). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (). |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017] |
UniProt Code: | Q7Z7B1 |
NCBI GenInfo Identifier: | 1092878785 |
NCBI Gene ID: | 284098 |
NCBI Accession: | NP_001333683.1 |
UniProt Secondary Accession: | Q7Z7B1,Q8N9G3 |
UniProt Related Accession: | Q7Z7B1 |
Molecular Weight: | 56,882 Da |
NCBI Full Name: | phosphatidylinositol-glycan biosynthesis class W protein |
NCBI Synonym Full Names: | phosphatidylinositol glycan anchor biosynthesis class W |
NCBI Official Symbol: | PIGW |
NCBI Official Synonym Symbols: | Gwt1; HPMRS5 |
NCBI Protein Information: | phosphatidylinositol-glycan biosynthesis class W protein |
UniProt Protein Name: | Phosphatidylinositol-glycan biosynthesis class W protein |
UniProt Synonym Protein Names: | |
Protein Family: | Phosphatidylinositol-glycan biosynthesis class W protein |
UniProt Gene Name: | PIGW |
UniProt Entry Name: |