Phospho-MAPK15 (Thr175/Tyr177) Antibody (PACO24192)
- SKU:
- PACO24192
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | Phospho-MAPK15 (Thr175/Tyr177) Antibody (PACO24192) |
抗体コード: | PACO24192 |
サイズ: | 100ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
反応性: | Human, Mouse |
免疫原: | Peptide sequence around phosphorylation site of threonine 175 and tyrosine 177 (A-V-T(p)-E-Y(p)-V-A) derived from Human ERK8. |
憲法: | Liquid |
ストレージバッファ: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
精製方法: | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from Jurkat cells, using ERK8 (Phospho-Thr175+Tyr177) antibody. The lane on the right is treated with the synthesized peptide. |
バックグラウンド: | In vitro, phosphorylates MBP. |
シノニム: | EC 2.7.11.24; Extracellular signal-regulated kinase 8 |
UniProt Protein Function: | ERK7: In vitro, phosphorylates MBP. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.24; Protein kinase, CMGC; Kinase, protein; CMGC group; MAPK family; Erk7 subfamily Chromosomal Location of Human Ortholog: - Cellular Component: extracellular region; intracellular; nucleus Molecular Function:ATP binding; MAP kinase activity; protein binding; SH3 domain binding Biological Process: MAPKKK cascade; negative regulation of DNA replication; negative regulation of transcription from RNA polymerase II promoter; positive regulation of protein amino acid phosphorylation; positive regulation of protein catabolic process; positive regulation of protein ubiquitination; positive regulation of telomerase activity; positive regulation of telomere maintenance via telomerase; protein amino acid autophosphorylation; response to estradiol stimulus |
UniProt Code: | Q8TD08 |
NCBI GenInfo Identifier: | 74760462 |
NCBI Gene ID: | 225689 |
NCBI Accession: | Q8TD08.1 |
UniProt Secondary Accession: | Q8TD08,Q2TCF9, Q8N362, |
UniProt Related Accession: | Q8TD08 |
Molecular Weight: | |
NCBI Full Name: | Mitogen-activated protein kinase 15 |
NCBI Synonym Full Names: | mitogen-activated protein kinase 15 |
NCBI Official Symbol: | MAPK15 |
NCBI Official Synonym Symbols: | ERK7; ERK8 |
NCBI Protein Information: | mitogen-activated protein kinase 15 |
UniProt Protein Name: | Mitogen-activated protein kinase 15 |
UniProt Synonym Protein Names: | Extracellular signal-regulated kinase 7; ERK-7; Extracellular signal-regulated kinase 8; ERK-8 |
UniProt Gene Name: | MAPK15 |
UniProt Entry Name: | MK15_HUMAN |
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