PHACTR1 Antibody (PACO58845)
- SKU:
- PACO58845
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PHACTR1 Antibody (PACO58845) |
抗体コード: | PACO58845 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Recombinant Human Phosphatase and actin regulator 1 protein (263-387AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Hela whole cell lysate, Rat brain tissue, Mouse brain tissue. All lanes: PHACTR1 antibody at 6µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 67, 55 kDa. Observed band size: 67 kDa. |
![]() | IHC image of PACO58845 diluted at 1:400 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | IHC image of PACO58845 diluted at 1:400 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Plays a role in cell motility. Plays a role in the formation of tubules by endothelial cells. Regulates PPP1CA activity. Required for normal cell survival. |
シノニム: | Phosphatase and actin regulator 1, PHACTR1, KIAA1733 RPEL1 |
UniProt Protein Function: | PHACTR1: Belongs to the phosphatase and actin regulator family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Adaptor/scaffoldChromosomal Location of Human Ortholog: 6p24.1Cellular Component: synapse; cell junction; nucleus; cytosolMolecular Function: protein phosphatase type 1 regulator activity; protein phosphatase inhibitor activity; actin binding; protein phosphatase 1 bindingBiological Process: actomyosin structure organization and biogenesis; actin cytoskeleton reorganization; negative regulation of catalytic activity; stress fiber formation; cell motility involved in cell locomotion |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9C0D0 |
NCBI GenInfo Identifier: | 336391125 |
NCBI Gene ID: | 221692 |
NCBI Accession: | NP_001229577.1 |
UniProt Secondary Accession: | Q9C0D0,Q3MJ93, Q5JSJ2, A8K1V2 |
UniProt Related Accession: | Q9C0D0 |
Molecular Weight: | 66,308 Da |
NCBI Full Name: | phosphatase and actin regulator 1 |
NCBI Synonym Full Names: | phosphatase and actin regulator 1 |
NCBI Official Symbol: | PHACTR1 |
NCBI Official Synonym Symbols: | RPEL; RPEL1; dJ257A7.2 |
NCBI Protein Information: | phosphatase and actin regulator 1; RPEL repeat containing 1 |
UniProt Protein Name: | Phosphatase and actin regulator 1 |
UniProt Synonym Protein Names: | |
Protein Family: | Phosphatase and actin regulator |
UniProt Gene Name: | PHACTR1 |
UniProt Entry Name: | PHAR1_HUMAN |