PGAM5 Antibody, HRP conjugated (PACO51283)
- SKU:
- PACO51283
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | PGAM5 Antibody, HRP conjugated (PACO51283) |
抗体コード: | PACO51283 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Serine/threonine-protein phosphatase PGAM5, mitochondrial protein (30-223AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. |
シノニム: | Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Bcl-XL-binding protein v68) (Phosphoglycerate mutase family member 5), PGAM5 |
UniProt Protein Function: | PGAM5: Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2- dependent gene expression. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Hydrolase; EC 3.1.3.16; Mitochondrial Chromosomal Location of Human Ortholog: 12q24.33 Cellular Component: integral to membrane; mitochondrial outer membrane; mitochondrion Molecular Function:GTPase activator activity; phosphoric monoester hydrolase activity; protein complex binding; receptor signaling protein serine/threonine phosphatase activity Biological Process: dephosphorylation; positive regulation of GTPase activity; protein amino acid dephosphorylation |
UniProt Code: | Q96HS1 |
NCBI GenInfo Identifier: | 281604151 |
NCBI Gene ID: | 192111 |
NCBI Accession: | NP_612642.2 |
UniProt Secondary Accession: | Q96HS1,Q96JB0, A9LN06, C9IZY7, |
UniProt Related Accession: | Q96HS1 |
Molecular Weight: | 28,020 Da |
NCBI Full Name: | serine/threonine-protein phosphatase PGAM5, mitochondrial isoform 3 |
NCBI Synonym Full Names: | PGAM family member 5, mitochondrial serine/threonine protein phosphatase |
NCBI Official Symbol: | PGAM5 |
NCBI Official Synonym Symbols: | BXLBV68 |
NCBI Protein Information: | serine/threonine-protein phosphatase PGAM5, mitochondrial |
UniProt Protein Name: | Serine/threonine-protein phosphatase PGAM5, mitochondrial |
UniProt Synonym Protein Names: | Bcl-XL-binding protein v68; Phosphoglycerate mutase family member 5 |
Protein Family: | Serine/threonine-protein phosphatase |
UniProt Gene Name: | PGAM5 |
UniProt Entry Name: | PGAM5_HUMAN |