PFDN6 Antibody (PACO19189)
- SKU:
- PACO19189
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PFDN6 Antibody (PACO19189) |
抗体コード: | PACO19189 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
反応性: | Human, Mouse |
免疫原: | Synthetic peptide of human PFDN6 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19189(PFDN6 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: PACO19189(PFDN6 Antibody) at dilution 1/250 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO19189(PFDN6 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | PFDN6 is a subunit of the heteromeric prefoldin complex that chaperones nascent actin (see MIM 102560) and alpha- and beta-tubulin (see MIM 602529 and MIM 191130, respectively) chains pending their transfer to the cytosolic chaperonin containing TCP1 (MIM 186980) (CCT) complex (Hansen et al., 1999 [PubMed 10209023]). |
シノニム: | prefoldin subunit 6 |
UniProt Protein Function: | PFDN6: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Belongs to the prefoldin subunit beta family. |
UniProt Protein Details: | Protein type:Chaperone; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 6p21.32 Cellular Component: cytoplasm; prefoldin complex Molecular Function:chaperone binding Biological Process: chaperone-mediated protein complex assembly; protein folding |
NCBI Summary: | PFDN6 is a subunit of the heteromeric prefoldin complex that chaperones nascent actin (see MIM 102560) and alpha- and beta-tubulin (see MIM 602529 and MIM 191130, respectively) chains pending their transfer to the cytosolic chaperonin containing TCP1 (MIM 186980) (CCT) complex (Hansen et al., 1999 [PubMed 10209023]).[supplied by OMIM, Jul 2010] |
UniProt Code: | O15212 |
NCBI GenInfo Identifier: | 6016432 |
NCBI Gene ID: | 10471 |
NCBI Accession: | O15212.1 |
UniProt Related Accession: | O15212 |
Molecular Weight: | Calculated: 14kDaObserved: 14kDa |
NCBI Full Name: | Prefoldin subunit 6 |
NCBI Synonym Full Names: | prefoldin subunit 6 |
NCBI Official Symbol: | PFDN6 |
NCBI Official Synonym Symbols: | HKE2; KE-2; PFD6; H2-KE2 |
NCBI Protein Information: | prefoldin subunit 6 |
UniProt Protein Name: | Prefoldin subunit 6 |
UniProt Synonym Protein Names: | Protein Ke2 |
Protein Family: | Prefoldin |
UniProt Gene Name: | PFDN6 |
Antibodies |
Anti-PFDN6 Antibody (CAB10580) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |