PDLIM5 Antibody, HRP conjugated (PACO46827)
- SKU:
- PACO46827
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | PDLIM5 Antibody, HRP conjugated (PACO46827) |
抗体コード: | PACO46827 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human PDZ and LIM domain protein 5 protein (268-404AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses (By similarity). |
シノニム: | PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein), PDLIM5, ENH |
UniProt Protein Function: | LIM: an adaptor protein of the Enigma family. Contains three LIM domains and one PDZ domain. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. Enigma family proteins possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 4q22 Cellular Component: postsynaptic membrane; neuron projection; membrane; postsynaptic density; cell junction; Z disc; cytosol; actin cytoskeleton Molecular Function:actinin binding; protein kinase C binding; zinc ion binding; protein N-terminus binding; actin binding Biological Process: regulation of synaptogenesis |
NCBI Summary: | This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
UniProt Code: | Q96HC4 |
NCBI GenInfo Identifier: | 317373590 |
NCBI Gene ID: | 10611 |
NCBI Accession: | Q96HC4.5 |
UniProt Secondary Accession: | Q96HC4,O60705, Q56VN4, Q5UW38, Q8WVK0, A8K6F9, D6RB78 E9PBF5, |
UniProt Related Accession: | Q96HC4 |
Molecular Weight: | 63,945 Da |
NCBI Full Name: | PDZ and LIM domain protein 5 |
NCBI Synonym Full Names: | PDZ and LIM domain 5 |
NCBI Official Symbol: | PDLIM5 |
NCBI Official Synonym Symbols: | L9; ENH; LIM; ENH1 |
NCBI Protein Information: | PDZ and LIM domain protein 5; enigma homolog; enigma-like LIM domain protein; enigma-like PDZ and LIM domains protein |
UniProt Protein Name: | PDZ and LIM domain protein 5 |
UniProt Synonym Protein Names: | Enigma homolog; Enigma-like PDZ and LIM domains protein |
UniProt Gene Name: | PDLIM5 |
UniProt Entry Name: | PDLI5_HUMAN |