PDLIM3 Antibody (PACO11146)
- SKU:
- PACO11146
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PDLIM3 Antibody (PACO11146) |
抗体コード: | PACO11146 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human PDLIM3 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | PDZ and LIM domain 3;PDLIM3;ALP;DKFZp686L0362 ; |
UniProt Protein Function: | PDLIM3: May play a role in the organization of actin filament arrays within muscle cells. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 4q35 Cellular Component: cytoplasm; Z disc; actin cytoskeleton Molecular Function:protein binding; zinc ion binding; structural constituent of muscle; cytoskeletal protein binding Biological Process: heart development; actin filament organization |
NCBI Summary: | The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012] |
UniProt Code: | Q53GG5 |
NCBI GenInfo Identifier: | 74740479 |
NCBI Gene ID: | 27295 |
NCBI Accession: | Q53GG5.1 |
UniProt Secondary Accession: | Q53GG5,O43590, O60439, O60440, Q8N6Y6, Q9BVP4, B2R866 |
UniProt Related Accession: | Q53GG5 |
Molecular Weight: | 364 |
NCBI Full Name: | PDZ and LIM domain protein 3 |
NCBI Synonym Full Names: | PDZ and LIM domain 3 |
NCBI Official Symbol: | PDLIM3 |
NCBI Official Synonym Symbols: | ALP |
NCBI Protein Information: | PDZ and LIM domain protein 3; enigma homolog; alpha-actinin-2-associated LIM protein |
UniProt Protein Name: | PDZ and LIM domain protein 3 |
UniProt Synonym Protein Names: | Actinin-associated LIM protein; Alpha-actinin-2-associated LIM protein |
Protein Family: | PDZ and LIM domain protein |
UniProt Gene Name: | PDLIM3 |
UniProt Entry Name: | PDLI3_HUMAN |