PCDHB16 Antibody (PACO15201)
- SKU:
- PACO15201
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PCDHB16 Antibody (PACO15201) |
抗体コード: | PACO15201 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Fusion protein of human PCDHB16 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO15201(PCDHB16 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | This gene is a member of the protocadherin β gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The β cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the α and γ clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. |
シノニム: | protocadherin β 16 |
UniProt Protein Function: | PCDHB16: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 5q31 Cellular Component: integral to membrane; plasma membrane Molecular Function:calcium ion binding Biological Process: synaptic transmission; synaptogenesis; calcium-dependent cell-cell adhesion; homophilic cell adhesion |
NCBI Summary: | This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NRJ7 |
NCBI GenInfo Identifier: | 605052038 |
NCBI Gene ID: | 57717 |
NCBI Accession: | NP_066008.2 |
UniProt Secondary Accession: | Q9NRJ7,Q8IYD5, Q96SE9, Q9HCF1, B3KPK5, |
UniProt Related Accession: | Q9NRJ7 |
Molecular Weight: | 84,983 Da |
NCBI Full Name: | protocadherin beta-16 |
NCBI Synonym Full Names: | protocadherin beta 16 |
NCBI Official Symbol: | PCDHB16 |
NCBI Official Synonym Symbols: | ME1; PCDH3X; PCDHB8a; PCDH-BETA16 |
NCBI Protein Information: | protocadherin beta-16; cadherin ME1; protocadherin beta 8a; protocadherin-3x |
UniProt Protein Name: | Protocadherin beta-16 |
UniProt Synonym Protein Names: | Protocadherin-3X |
Protein Family: | Protocadherin |
UniProt Gene Name: | PCDHB16 |
UniProt Entry Name: | PCDBG_HUMAN |
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