PCDHA10 Antibody (PACO64439)
- SKU:
- PACO64439
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PCDHA10 Antibody (PACO64439) |
抗体コード: | PACO64439 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IF |
推奨される希釈: | IF:1:100-1:500 |
反応性: | Human |
免疫原: | Recombinant Human Protocadherin alpha-10 protein (276-324AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescence staining of SH-SY5Y cells with PACO64439 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. |
シノニム: | Protocadherin alpha-10 (PCDH-alpha-10), PCDHA10, CNRS8 |
UniProt Protein Function: | PCDHA10: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 5q31 Cellular Component: integral to plasma membrane Biological Process: cell adhesion; nervous system development |
NCBI Summary: | This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y5I2 |
NCBI GenInfo Identifier: | 13878433 |
NCBI Gene ID: | 56139 |
NCBI Accession: | Q9Y5I2.1 |
UniProt Secondary Accession: | Q9Y5I2,O75280, Q9NRU2, A1L493, |
UniProt Related Accession: | Q9Y5I2 |
Molecular Weight: | 92,185 Da |
NCBI Full Name: | Protocadherin alpha-10 |
NCBI Synonym Full Names: | protocadherin alpha 10 |
NCBI Official Symbol: | PCDHA10 |
NCBI Official Synonym Symbols: | CNR8; CNRN8; CNRS8; CRNR8; PCDH-ALPHA10 |
NCBI Protein Information: | protocadherin alpha-10 |
UniProt Protein Name: | Protocadherin alpha-10 |
Protein Family: | Protocadherin |
UniProt Gene Name: | PCDHA10 |
UniProt Entry Name: | PCDAA_HUMAN |
Antibodies |
Anti-PCDHA10 Antibody (CAB17185) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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