Paox Antibody, HRP conjugated (PACO37583)
- SKU:
- PACO37583
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | Paox Antibody, HRP conjugated (PACO37583) |
抗体コード: | PACO37583 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Mouse |
免疫原: | Recombinant Mouse Peroxisomal N(1)-acetyl-spermine/spermidine oxidase protein (1-504AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. |
シノニム: | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase), Paox, Pao |
UniProt Protein Function: | PAOX: Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. Belongs to the flavin monoamine oxidase family. 11 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.5.3.13; OxidoreductaseChromosomal Location of Human Ortholog: 7|7 F4Cellular Component: cytoplasm; peroxisomal matrix; peroxisomeMolecular Function: oxidoreductase activity; polyamine oxidase activity; receptor bindingBiological Process: polyamine catabolic process; putrescine biosynthetic process; putrescine catabolic process; spermidine catabolic process; spermine catabolic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8C0L6 |
NCBI GenInfo Identifier: | 28173566 |
NCBI Gene ID: | 212503 |
NCBI Accession: | NP_722478.2 |
UniProt Secondary Accession: | Q8C0L6,Q8K254 |
UniProt Related Accession: | Q8C0L6 |
Molecular Weight: | |
NCBI Full Name: | peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 1 |
NCBI Synonym Full Names: | polyamine oxidase (exo-N4-amino) |
NCBI Official Symbol: | Paox |
NCBI Official Synonym Symbols: | Pao; AI118225; 2410012F02Rik |
NCBI Protein Information: | peroxisomal N(1)-acetyl-spermine/spermidine oxidase |
UniProt Protein Name: | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase |
UniProt Synonym Protein Names: | Polyamine oxidase |
Protein Family: | Polyamine oxidase |
UniProt Gene Name: | Paox |
UniProt Entry Name: |