PAFAH2 Antibody (PACO18803)
- SKU:
- PACO18803
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PAFAH2 Antibody (PACO18803) |
抗体コード: | PACO18803 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:100-1:300 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human PAFAH2 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: 231 cells, Primary antibody: PACO18803(PAFAH2 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18803(PAFAH2 Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. |
シノニム: | platelet-activating factor acetylhydrolase 2, 40kDa |
UniProt Protein Function: | PAFAH2: Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme. Belongs to the serine esterase family. |
UniProt Protein Details: | Protein type:Hydrolase; Lipid-binding; EC 3.1.1.47; Lipid Metabolism - ether lipid Chromosomal Location of Human Ortholog: 1p36 Molecular Function:phospholipid binding Biological Process: lipid metabolic process |
NCBI Summary: | This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99487 |
NCBI GenInfo Identifier: | 6647691 |
NCBI Gene ID: | 5051 |
NCBI Accession: | Q99487.1 |
UniProt Secondary Accession: | Q99487,O15458, Q5SY02, D3DPK1, |
UniProt Related Accession: | Q99487 |
Molecular Weight: | 44,036 Da |
NCBI Full Name: | Platelet-activating factor acetylhydrolase 2, cytoplasmic |
NCBI Synonym Full Names: | platelet activating factor acetylhydrolase 2 |
NCBI Official Symbol: | PAFAH2 |
NCBI Official Synonym Symbols: | HSD-PLA2 |
NCBI Protein Information: | platelet-activating factor acetylhydrolase 2, cytoplasmic |
UniProt Protein Name: | Platelet-activating factor acetylhydrolase 2, cytoplasmic |
UniProt Synonym Protein Names: | Serine-dependent phospholipase A2; SD-PLA2; hSD-PLA2 |
Protein Family: | Platelet-activating factor acetylhydrolase |
UniProt Gene Name: | PAFAH2 |
UniProt Entry Name: | PAFA2_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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