PADI1 Antibody, HRP conjugated (PACO42383)
- SKU:
- PACO42383
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | PADI1 Antibody, HRP conjugated (PACO42383) |
抗体コード: | PACO42383 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Protein-arginine deiminase type-1 protein (1-663AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Catalyzes the deimination of arginine residues of proteins. |
シノニム: | Protein-arginine deiminase type-1 (EC 3.5.3.15) (Peptidylarginine deiminase I) (Protein-arginine deiminase type I), PADI1, PAD1 PDI1 |
UniProt Protein Function: | Function: Catalyzes the deimination of arginine residues of proteins |
UniProt Protein Details: | By similarity. Catalytic activity: Protein L-arginine + H2O = protein L-citrulline + NH3. Cofactor: Calcium By similarity. Subcellular location: Cytoplasm Ref.1. Tissue specificity: Epidermis, prostate, testis, placenta, spleen and thymus. Ref.1 Sequence similarities: Belongs to the protein arginine deiminase family. |
NCBI Summary: | This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9ULC6 |
NCBI GenInfo Identifier: | 122056684 |
NCBI Gene ID: | 29943 |
NCBI Accession: | NP_037490.2 |
UniProt Secondary Accession: | Q9ULC6,Q70SX6, A1L4K6, |
UniProt Related Accession: | Q9ULC6 |
Molecular Weight: | 95 kDa |
NCBI Full Name: | Homo sapiens peptidyl arginine deiminase, type I (PADI1), mRNA |
NCBI Synonym Full Names: | peptidyl arginine deiminase, type I |
NCBI Official Symbol: | PADI1 |
NCBI Official Synonym Symbols: | PDI; PAD1; PDI1; HPAD10 |
NCBI Protein Information: | protein-arginine deiminase type-1; hPAD-colony 10; peptidylarginine deiminase I; protein-arginine deiminase type I |
UniProt Protein Name: | Protein-arginine deiminase type-1 |
UniProt Synonym Protein Names: | Peptidylarginine deiminase I; Protein-arginine deiminase type I |
Protein Family: | Proteasome |
UniProt Gene Name: | PADI1 |
UniProt Entry Name: | PADI1_HUMAN |