PACS2 Antibody, FITC conjugated (PACO57910)
- SKU:
- PACO57910
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | PACS2 Antibody, FITC conjugated (PACO57910) |
抗体コード: | PACO57910 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Phosphofurin acid, c cluster sorting protein 2 protein (268-465AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acid, c cluster-containing ion channels to distinct subcellular compartments. |
シノニム: | Phosphofurin acid, c cluster sorting protein 2 (PACS-2) (PACS1-like protein), PACS2, KIAA0602 PACS1L |
UniProt Protein Function: | PACS2: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. Belongs to the PACS family. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 14q32.33Cellular Component: endoplasmic reticulumBiological Process: autophagic vacuole formation |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q86VP3 |
NCBI GenInfo Identifier: | 117949768 |
NCBI Gene ID: | 23241 |
NCBI Accession: | Q86VP3.3 |
UniProt Secondary Accession: | Q86VP3,O60342, Q6P191, Q96FL7, A2VDJ9, G8JLK3 |
UniProt Related Accession: | Q86VP3 |
Molecular Weight: | 89,609 Da |
NCBI Full Name: | Phosphofurin acidic cluster sorting protein 2 |
NCBI Synonym Full Names: | phosphofurin acidic cluster sorting protein 2 |
NCBI Official Symbol: | PACS2 |
NCBI Official Synonym Symbols: | PACS-2; PACS1L |
NCBI Protein Information: | phosphofurin acidic cluster sorting protein 2 |
UniProt Protein Name: | Phosphofurin acidic cluster sorting protein 2 |
UniProt Synonym Protein Names: | PACS1-like protein |
Protein Family: | Phosphofurin acidic cluster sorting protein |
UniProt Gene Name: | PACS2 |
UniProt Entry Name: | PACS2_HUMAN |