P4HA3 Antibody, Biotin conjugated (PACO37389)
- SKU:
- PACO37389
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | P4HA3 Antibody, Biotin conjugated (PACO37389) |
抗体コード: | PACO37389 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Prolyl 4-hydroxylase subunit alpha-3 protein (20-544AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. |
シノニム: | Prolyl 4-hydroxylase subunit alpha-3 (4-PH alpha-3) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3), P4HA3 |
UniProt Protein Function: | P4HA3: Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. Belongs to the P4HA family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted; Amino Acid Metabolism - arginine and proline; Oxidoreductase; EC 1.14.11.2; Secreted, signal peptide Chromosomal Location of Human Ortholog: 11q13.4 Molecular Function:protein binding |
NCBI Summary: | This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
UniProt Code: | Q7Z4N8 |
NCBI GenInfo Identifier: | 74738714 |
NCBI Gene ID: | 283208 |
NCBI Accession: | Q7Z4N8.1 |
UniProt Secondary Accession: | Q7Z4N8,Q5EBL3, Q5JPA9, A0AV13, B4DUD3, |
UniProt Related Accession: | Q7Z4N8 |
Molecular Weight: | 67,591 Da |
NCBI Full Name: | Prolyl 4-hydroxylase subunit alpha-3 |
NCBI Synonym Full Names: | prolyl 4-hydroxylase subunit alpha 3 |
NCBI Official Symbol: | P4HA3 |
NCBI Protein Information: | prolyl 4-hydroxylase subunit alpha-3 |
UniProt Protein Name: | Prolyl 4-hydroxylase subunit alpha-3 |
UniProt Synonym Protein Names: | Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3 |
Protein Family: | Prolyl 4-hydroxylase |
UniProt Gene Name: | P4HA3 |
UniProt Entry Name: | P4HA3_HUMAN |