ONECUT1 Antibody, HRP conjugated (PACO57509)
- SKU:
- PACO57509
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | ONECUT1 Antibody, HRP conjugated (PACO57509) |
抗体コード: | PACO57509 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Hepatocyte nuclear factor 6 protein (192-292AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription. |
シノニム: | Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) (One cut homeobox 1), ONECUT1, HNF6 HNF6A |
UniProt Protein Function: | ONECUT1: Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription. Belongs to the CUT homeobox family. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 15q21.3 Cellular Component: nucleus Molecular Function:DNA binding Biological Process: spleen development; cell fate commitment; transcription, DNA-dependent; regulation of cell-matrix adhesion; system development; glucose metabolic process; liver development; endocrine pancreas development; regulation of transcription, DNA-dependent; B cell differentiation; epithelial cell development; cilium biogenesis; positive regulation of transcription from RNA polymerase II promoter; cell differentiation; negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of cell migration; endoderm development |
NCBI Summary: | This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] |
UniProt Code: | Q9UBC0 |
NCBI GenInfo Identifier: | 13627184 |
NCBI Gene ID: | 3175 |
NCBI Accession: | Q9UBC0.1 |
UniProt Related Accession: | Q9UBC0 |
Molecular Weight: | |
NCBI Full Name: | Hepatocyte nuclear factor 6 |
NCBI Synonym Full Names: | one cut homeobox 1 |
NCBI Official Symbol: | ONECUT1 |
NCBI Official Synonym Symbols: | HNF6; HNF-6; HNF6A |
NCBI Protein Information: | hepatocyte nuclear factor 6 |
UniProt Protein Name: | Hepatocyte nuclear factor 6 |
UniProt Synonym Protein Names: | One cut domain family member 1; One cut homeobox 1 |
UniProt Gene Name: | ONECUT1 |
UniProt Entry Name: | HNF6_HUMAN |