NUP58 Antibody, HRP conjugated (PACO42115)
- SKU:
- PACO42115
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | NUP58 Antibody, HRP conjugated (PACO42115) |
抗体コード: | PACO42115 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Nucleoporin p58/p45 protein (211-480AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. |
シノニム: | Nucleoporin p58/p45 (58 kDa nucleoporin) (Nucleoporin-like protein 1), NUP58, KIAA0410 NUPL1 |
UniProt Protein Function: | NUPL1: a nuclear pore protein. Component of the p62 complex which includes NUP62, NUP54, and NUPL1. Interacts with NUTF2, and with KPNA2 and KPNB1 proteins when they are together, but not with KPNA2 alone. Located in the central region of the nuclear pore complex, biased towards thecytoplasmic side. Contains FG repeats. Three isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nucleoporin; Nuclear import Chromosomal Location of Human Ortholog: 13q12.13 Cellular Component: nuclear envelope; nuclear pore Molecular Function:nuclear localization sequence binding; nucleocytoplasmic transporter activity; protein binding Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; protein import into nucleus; protein sumoylation; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription |
NCBI Summary: | This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9BVL2 |
NCBI GenInfo Identifier: | 44888845 |
NCBI Gene ID: | 9818 |
NCBI Accession: | Q9BVL2.1 |
UniProt Secondary Accession: | Q9BVL2,O43160, Q5JRG2, Q5JRG5, A6NI12, B4DZJ1, |
UniProt Related Accession: | Q9BVL2 |
Molecular Weight: | 59,754 Da |
NCBI Full Name: | Nucleoporin p58/p45 |
NCBI Synonym Full Names: | nucleoporin 58 |
NCBI Official Symbol: | NUP58 |
NCBI Official Synonym Symbols: | NUP45; NUPL1; PRO2463 |
NCBI Protein Information: | nucleoporin p58/p45 |
UniProt Protein Name: | Nucleoporin p58/p45 |
UniProt Synonym Protein Names: | 58 kDa nucleoporin |
UniProt Gene Name: | NUP58 |
UniProt Entry Name: | NUP58_HUMAN |