NTSR1 Antibody, HRP conjugated (PACO54919)
- SKU:
- PACO54919
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Description
抗体名: | NTSR1 Antibody, HRP conjugated (PACO54919) |
抗体コード: | PACO54919 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Neurotensin receptor type 1 protein (1-67AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | G-protein coupled receptor for the tridecapeptide neurotensin (NTS). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis. |
シノニム: | Neurotensin receptor type 1 (NT-R-1) (NTR1) (High-affinity levocabastine-insensitive neurotensin receptor) (NTRH), NTSR1, NTRR |
UniProt Protein Function: | NTSR1: Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Neurotensin receptor subfamily. NTSR1 sub-subfamily. |
UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 20q13 Cellular Component: cell surface; dendritic shaft; dendritic spine; endoplasmic reticulum; Golgi apparatus; integral to plasma membrane; internal side of plasma membrane; lipid raft; mitochondrion; perikaryon; plasma membrane; terminal button Molecular Function:G-protein coupled receptor activity; neurotensin receptor activity, G-protein coupled; protein binding; protein heterodimerization activity; protein homodimerization activity; protein N-terminus binding Biological Process: adult locomotory behavior; detection of temperature stimulus involved in sensory perception of pain; G-protein coupled receptor protein signaling pathway; learning; negative regulation of apoptosis; negative regulation of release of sequestered calcium ion into cytosol; negative regulation of systemic arterial blood pressure; neuropeptide signaling pathway; positive regulation of apoptosis; positive regulation of gamma-aminobutyric acid secretion; positive regulation of glutamate secretion; positive regulation of release of sequestered calcium ion into cytosol; regulation of respiratory gaseous exchange; regulation of sensory perception of pain; response to lipid; synaptic transmission; thermoregulation |
NCBI Summary: | Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008] |
UniProt Code: | P30989 |
NCBI GenInfo Identifier: | 62297312 |
NCBI Gene ID: | 4923 |
NCBI Accession: | P30989.2 |
UniProt Secondary Accession: | P30989,Q9H4H1, Q9H4T5, |
UniProt Related Accession: | P30989 |
Molecular Weight: | 46,259 Da |
NCBI Full Name: | Neurotensin receptor type 1 |
NCBI Synonym Full Names: | neurotensin receptor 1 (high affinity) |
NCBI Official Symbol: | NTSR1 |
NCBI Official Synonym Symbols: | NTR |
NCBI Protein Information: | neurotensin receptor type 1 |
UniProt Protein Name: | Neurotensin receptor type 1 |
UniProt Synonym Protein Names: | High-affinity levocabastine-insensitive neurotensin receptor; NTRH |
Protein Family: | Neurotensin receptor |
UniProt Gene Name: | NTSR1 |
UniProt Entry Name: | NTR1_HUMAN |