NRTN Antibody (PACO18788)
- SKU:
- PACO18788
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NRTN Antibody (PACO18788) |
抗体コード: | PACO18788 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
反応性: | Human, Mouse |
免疫原: | Synthetic peptide of human NRTN |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO18788(NRTN Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18788(NRTN Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Neurturin is a member of the TGF-β subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. |
シノニム: | neurturin |
UniProt Protein Function: | NRTN: Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells. Genetic variations in NRTN may contribute to Hirschsprung disease, in association with mutations of RET gene, and possibly mutations in other loci. Hirschsprung disease is a disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction. Belongs to the TGF-beta family. GDNF subfamily. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: axon; extracellular region Molecular Function:growth factor activity; receptor binding Biological Process: axon guidance; nervous system development; MAPKKK cascade; nerve development; neural crest cell migration; neurite development; transmembrane receptor protein tyrosine kinase signaling pathway Disease: Hirschsprung Disease, Susceptibility To, 1 |
NCBI Summary: | Neurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99748 |
NCBI GenInfo Identifier: | 2501180 |
NCBI Gene ID: | 4902 |
NCBI Accession: | Q99748.1 |
UniProt Secondary Accession: | Q99748,B2RPE8, |
UniProt Related Accession: | Q99748 |
Molecular Weight: | 22,405 Da |
NCBI Full Name: | Neurturin |
NCBI Synonym Full Names: | neurturin |
NCBI Official Symbol: | NRTN |
NCBI Official Synonym Symbols: | NTN |
NCBI Protein Information: | neurturin; prepro-neurturin |
UniProt Protein Name: | Neurturin |
Protein Family: | Neurturin |
UniProt Gene Name: | NRTN |
UniProt Entry Name: | NRTN_HUMAN |
Antibodies | ELISA Kits |
Anti-NRTN Antibody (CAB16409) | Human NRTN / Neurturin ELISA Kit |
NRTN Antibody (PACO06924) | Human Neurturin (NRTN) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |