NR2F1 Antibody (PACO58829)
- SKU:
- PACO58829
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NR2F1 Antibody (PACO58829) |
抗体コード: | PACO58829 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
反応性: | Human |
免疫原: | Recombinant Human COUP transcription factor 1 protein (178-421AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: A549 whole cell lysate. All lanes: NR2F1 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa. |
バックグラウンド: | Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. Represses transcriptional activity of LHCG. |
シノニム: | COUP transcription factor 1 (COUP-TF1) (COUP transcription factor I) (COUP-TF I) (Nuclear receptor subfamily 2 group F member 1) (V-erbA-related protein 3) (EAR-3), NR2F1, EAR3 ERBAL3 TFCOUP1 |
UniProt Protein Function: | NR2F1: Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. Represses transcriptional activity of LHCG. Binds DNA as dimer; homodimer and probable heterodimer with NR2F6. Interacts with COPS2. Inhibited by gonadotropin in granulosa cells. Belongs to the nuclear hormone receptor family. NR2 subfamily. |
UniProt Protein Details: | Protein type:DNA-binding; Nuclear receptor; Transcription factor Chromosomal Location of Human Ortholog: 5q14 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; sequence-specific DNA binding; transcription coactivator activity; transcription factor activity Biological Process: negative regulation of transcription from RNA polymerase II promoter; signal transduction; transcription initiation from RNA polymerase II promoter Disease: Bosch-boonstra-schaaf Optic Atrophy Syndrome |
NCBI Summary: | The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS). [provided by RefSeq, Apr 2014] |
UniProt Code: | P10589 |
NCBI GenInfo Identifier: | 116959 |
NCBI Gene ID: | 7025 |
NCBI Accession: | P10589.1 |
UniProt Related Accession: | P10589 |
Molecular Weight: | 46,156 Da |
NCBI Full Name: | COUP transcription factor 1 |
NCBI Synonym Full Names: | nuclear receptor subfamily 2 group F member 1 |
NCBI Official Symbol: | NR2F1 |
NCBI Official Synonym Symbols: | EAR3; BBOAS; EAR-3; NR2F2; SVP44; BBSOAS; ERBAL3; TFCOUP1; COUP-TFI; TCFCOUP1 |
NCBI Protein Information: | COUP transcription factor 1 |
UniProt Protein Name: | COUP transcription factor 1 |
UniProt Synonym Protein Names: | COUP transcription factor I; COUP-TF I; Nuclear receptor subfamily 2 group F member 1; V-erbA-related protein 3; EAR-3 |
Protein Family: | COUP transcription factor |
UniProt Gene Name: | NR2F1 |
UniProt Entry Name: | COT1_HUMAN |
Antibodies |
Anti-NR2F1 Antibody (CAB16437) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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