NOVA1 Antibody (PACO55694)
- SKU:
- PACO55694
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NOVA1 Antibody (PACO55694) |
抗体コード: | PACO55694 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human RNA-binding protein Nova-1 protein (6-174AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Jurkat whole cell lysate. All lanes: NOVA1 antibody at 2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 53, 20, 50, 52 kDa. Observed band size: 53, 50 kDa. | |
IHC image of PACO55694 diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | May regulate RNA splicing or metabolism in a specific subset of developing neurons. |
シノニム: | RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1), NOVA1 |
UniProt Protein Function: | NOVA1: May regulate RNA splicing or metabolism in a specific subset of developing neurons. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding; RNA splicing Chromosomal Location of Human Ortholog: 14q Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus Molecular Function:RNA binding Biological Process: locomotory behavior; RNA processing; RNA splicing; synaptic transmission |
NCBI Summary: | This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | P51513 |
NCBI GenInfo Identifier: | 1709303 |
NCBI Gene ID: | 4857 |
NCBI Accession: | P51513.1 |
UniProt Secondary Accession: | P51513,Q6B004, A8K0S4, A8K4Q7, D3DS81, D3DS82, |
UniProt Related Accession: | P51513 |
Molecular Weight: | 49,253 Da |
NCBI Full Name: | RNA-binding protein Nova-1 |
NCBI Synonym Full Names: | NOVA alternative splicing regulator 1 |
NCBI Official Symbol: | NOVA1 |
NCBI Official Synonym Symbols: | Nova-1 |
NCBI Protein Information: | RNA-binding protein Nova-1 |
UniProt Protein Name: | RNA-binding protein Nova-1 |
UniProt Synonym Protein Names: | Neuro-oncological ventral antigen 1; Onconeural ventral antigen 1; Paraneoplastic Ri antigen; Ventral neuron-specific protein 1 |
Protein Family: | RNA-binding protein |
UniProt Gene Name: | NOVA1 |
UniProt Entry Name: | NOVA1_HUMAN |
Antibodies |
Anti-NOVA1 Antibody (CAB12030) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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