NOSTRIN Antibody, Biotin conjugated (PACO37857)
- SKU:
- PACO37857
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | NOSTRIN Antibody, Biotin conjugated (PACO37857) |
抗体コード: | PACO37857 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Nostrin protein (1-322AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. |
シノニム: | Nostrin (BM247 homolog) (Nitric oxide synthase traffic inducer) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer), NOSTRIN |
UniProt Protein Function: | NOSTRIN: Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 2q31.1 Cellular Component: plasma membrane Molecular Function:protein binding Biological Process: regulation of nitric-oxide synthase activity |
NCBI Summary: | Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004] |
UniProt Code: | Q8IVI9 |
NCBI GenInfo Identifier: | 317373401 |
NCBI Gene ID: | 115677 |
NCBI Accession: | Q8IVI9.2 |
UniProt Secondary Accession: | Q8IVI9,Q27HG3, Q53S62, Q96CJ9, A8K2I9, B3KSF5, E7EPT9 |
UniProt Related Accession: | Q8IVI9 |
Molecular Weight: | 64,364 Da |
NCBI Full Name: | Nostrin |
NCBI Synonym Full Names: | nitric oxide synthase trafficking |
NCBI Official Symbol: | NOSTRIN |
NCBI Official Synonym Symbols: | DaIP2 |
NCBI Protein Information: | nostrin |
UniProt Protein Name: | Nostrin |
UniProt Synonym Protein Names: | BM247 homolog; Nitric oxide synthase traffic inducer; Nitric oxide synthase trafficker; eNOS-trafficking inducer |
Protein Family: | Nostrin |
UniProt Gene Name: | NOSTRIN |
UniProt Entry Name: | NOSTN_HUMAN |