NME6 Antibody, FITC conjugated (PACO28584)
- SKU:
- PACO28584
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | NME6 Antibody, FITC conjugated (PACO28584) |
抗体コード: | PACO28584 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Nucleoside diphosphate kinase 6 protein (1-186AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP γ phosphate is transferred to the NDP β phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis. |
シノニム: | Nucleoside diphosphate kinase 6 (NDK 6) (NDP kinase 6) (EC 2.7.4.6) (Inhibitor of p53-induced apoptosis-alpha) (IPIA-alpha) (nm23-H6), NME6 |
UniProt Protein Function: | NME6: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis. Belongs to the NDK family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.7.4.6; Nucleotide Metabolism - pyrimidine; Kinase, nucleoside diphosphate; Nucleotide Metabolism - purine; Kinase, other; Other group; NDK family Chromosomal Location of Human Ortholog: 3p21 Cellular Component: mitochondrion Molecular Function:nucleoside diphosphate kinase activity Biological Process: negative regulation of cell growth; negative regulation of mitosis |
NCBI Summary: | Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates (Mehus et al., 1999 [PubMed 10453732]).[supplied by OMIM, Jul 2010] |
UniProt Code: | O75414 |
NCBI GenInfo Identifier: | 12232627 |
NCBI Gene ID: | 10201 |
NCBI Accession: | O75414.3 |
UniProt Secondary Accession: | O75414,Q53HM5, Q96E73, Q9BQ63, B4DGW7, B4DM99, |
UniProt Related Accession: | O75414 |
Molecular Weight: | 18,087 Da |
NCBI Full Name: | Nucleoside diphosphate kinase 6 |
NCBI Synonym Full Names: | NME/NM23 nucleoside diphosphate kinase 6 |
NCBI Official Symbol: | NME6 |
NCBI Official Synonym Symbols: | NDK 6; NM23-H6; IPIA-ALPHA |
NCBI Protein Information: | nucleoside diphosphate kinase 6 |
UniProt Protein Name: | Nucleoside diphosphate kinase 6 |
UniProt Synonym Protein Names: | Inhibitor of p53-induced apoptosis-alpha; IPIA-alpha; nm23-H6 |
Protein Family: | Nucleoside diphosphate kinase |
UniProt Gene Name: | NME6 |
UniProt Entry Name: | NDK6_HUMAN |