Nkx2-2 Antibody, HRP conjugated (PACO28575)
- SKU:
- PACO28575
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | Nkx2-2 Antibody, HRP conjugated (PACO28575) |
抗体コード: | PACO28575 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Mouse |
免疫原: | Recombinant Mouse Homeobox protein Nkx-2.2 protein (1-273AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter. |
シノニム: | Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B), Nkx2-2, Nkx-2.2 Nkx2b |
UniProt Protein Function: | NKX2-2: Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter. Belongs to the NK-2 homeobox family.Protein type: Cell development/differentiation; Transcription factorCellular Component: intracellular; nucleusMolecular Function: chromatin binding; DNA binding; protein binding; sequence-specific DNA binding; transcription coactivator activity; transcription factor activity; transcription factor bindingBiological Process: astrocyte differentiation; cell development; cell differentiation; endocrine pancreas development; gut development; multicellular organismal development; negative regulation of neuron differentiation; nervous system development; neuron fate specification; oligodendrocyte development; positive regulation of cell differentiation; positive regulation of neuron differentiation; positive regulation of oligodendrocyte differentiation; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; regulation of cell differentiation; regulation of transcription, DNA-dependent; smoothened signaling pathway; spinal cord motor neuron differentiation; spinal cord oligodendrocyte cell differentiation; spinal cord oligodendrocyte cell fate specification; transcription, DNA-dependent |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P42586 |
NCBI GenInfo Identifier: | 6754860 |
NCBI Gene ID: | 18088 |
NCBI Accession: | NP_035049.1 |
UniProt Secondary Accession: | P42586 |
UniProt Related Accession: | P42586 |
Molecular Weight: | 46.1 kDa |
NCBI Full Name: | homeobox protein Nkx-2.2 isoform 1 |
NCBI Synonym Full Names: | NK2 homeobox 2 |
NCBI Official Symbol: | Nkx2-2 |
NCBI Official Synonym Symbols: | Nkx2.2; tinman; Nkx-2.2 |
NCBI Protein Information: | homeobox protein Nkx-2.2 |
UniProt Protein Name: | Homeobox protein Nkx-2.2 |
UniProt Synonym Protein Names: | Homeobox protein NK-2 homolog B |
Protein Family: | Homeobox protein |
UniProt Gene Name: | Nkx2-2 |
UniProt Entry Name: | NKX22_MOUSE |