NKIRAS2 Antibody, Biotin conjugated (PACO41209)
- SKU:
- PACO41209
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | NKIRAS2 Antibody, Biotin conjugated (PACO41209) |
抗体コード: | PACO41209 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human NF-kappa-B inhibitor-interacting Ras-like protein 2 protein (1-191AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor β (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity). |
シノニム: | NF-kappa-B inhibitor-interacting Ras-like protein 2 (I-kappa-B-interacting Ras-like protein 2) (κ B-Ras protein 2) (KappaB-Ras2), NKIRAS2, KBRAS2 |
UniProt Protein Function: | NKIRAS2: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF- kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: G protein, monomeric, Ras; G protein; G protein, monomericChromosomal Location of Human Ortholog: 17q21.2 |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9NYR9 |
NCBI GenInfo Identifier: | 74734716 |
NCBI Gene ID: | 28511 |
NCBI Accession: | Q9NYR9.1 |
UniProt Secondary Accession: | Q9NYR9,Q6PK52, Q96KC7, Q9NSX1, A6NCZ5, B3KNN0, B4DNM3 |
UniProt Related Accession: | Q9NYR9 |
Molecular Weight: | 10,770 Da |
NCBI Full Name: | NF-kappa-B inhibitor-interacting Ras-like protein 2 |
NCBI Synonym Full Names: | NFKB inhibitor interacting Ras like 2 |
NCBI Official Symbol: | NKIRAS2 |
NCBI Official Synonym Symbols: | KBRAS2; kappaB-Ras2 |
NCBI Protein Information: | NF-kappa-B inhibitor-interacting Ras-like protein 2 |
UniProt Protein Name: | NF-kappa-B inhibitor-interacting Ras-like protein 2 |
UniProt Synonym Protein Names: | I-kappa-B-interacting Ras-like protein 2; Kappa B-Ras protein 2; KappaB-Ras2 |
Protein Family: | NF-kappa-B inhibitor-interacting Ras-like protein |
UniProt Gene Name: | NKIRAS2 |
UniProt Entry Name: | KBRS2_HUMAN |