UniProt Protein Function: | Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. |
NCBI Summary: | This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
UniProt Code: | Q13952 |
NCBI GenInfo Identifier: | 20137773 |
NCBI Gene ID: | 4802 |
NCBI Accession: | Q13952.3 |
UniProt Secondary Accession: | Q13952,Q59GY4, Q5T6K8, Q5T6K9, Q5T6L1, Q5TZR6, Q92869 Q9HBX1, B4DUS6, B4DW63, D3DPV9, F8VWM3, |
UniProt Related Accession: | Q13952 |
Molecular Weight: | 37,066 Da |
NCBI Full Name: | Nuclear transcription factor Y subunit gamma |
NCBI Synonym Full Names: | nuclear transcription factor Y subunit gamma |
NCBI Official Symbol: | NFYC |
NCBI Official Synonym Symbols: | HSM; CBFC; HAP5; CBF-C; NF-YC; H1TF2A |
NCBI Protein Information: | nuclear transcription factor Y subunit gamma |
UniProt Protein Name: | Nuclear transcription factor Y subunit gamma |
UniProt Synonym Protein Names: | CAAT box DNA-binding protein subunit C; Nuclear transcription factor Y subunit C; NF-YC; Transactivator HSM-1/2 |
Protein Family: | Nuclear transcription factor |
UniProt Gene Name: | NFYC |
UniProt Entry Name: | NFYC_HUMAN |