NEURL2 Antibody (PACO10824)
- SKU:
- PACO10824
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NEURL2 Antibody (PACO10824) |
抗体コード: | PACO10824 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human NEURL2 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | neuralized homolog 2 (Drosophila);NEURL2;C20orf163;MGC125934;MGC125935;OZZ;Ozz-E3 ; |
UniProt Protein Function: | NEURL2: Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system; Ligase; Ubiquitin ligase; EC 6.3.2.- Chromosomal Location of Human Ortholog: 20q13.12 Cellular Component: muscle tendon junction; VCB complex Biological Process: protein ubiquitination; sarcomere organization |
NCBI Summary: | This gene encodes a protein that is involved in the regulation of myofibril organization. This protein is likely the adaptor component of the E3 ubiquitin ligase complex in striated muscle, and it regulates the ubiquitin-mediated degradation of beta-catenin during myogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2013] |
UniProt Code: | Q9BR09 |
NCBI GenInfo Identifier: | 33301415 |
NCBI Gene ID: | |
NCBI Accession: | Q9BR09.1 |
UniProt Secondary Accession: | Q9BR09,Q3KR34, |
Molecular Weight: | 31,690 Da |
NCBI Full Name: | Neuralized-like protein 2 |
UniProt Protein Name: | Neuralized-like protein 2 |
Protein Family: | Neuralized-like protein |
UniProt Gene Name: | NEURL2 |
UniProt Entry Name: | NEUL2_HUMAN |