NCKAP1 Antibody (PACO10757)
- SKU:
- PACO10757
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | NCKAP1 Antibody (PACO10757) |
抗体コード: | PACO10757 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human NCKAP1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | NCK-associated protein 1;NCKAP1;FLJ11291;HEM2;KIAA0587;MGC8981;NAP1;NAP125 ; |
UniProt Protein Function: | NCKAP1: Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Belongs to the HEM-1/HEM-2 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Apoptosis; Motility/polarity/chemotaxis; Membrane protein, integral Chromosomal Location of Human Ortholog: 2q32 Cellular Component: focal adhesion; integral to membrane; cytosol Molecular Function:protein binding; Rac GTPase binding; protein complex binding Biological Process: lamellipodium biogenesis; somitogenesis; central nervous system development; basal protein localization; zygotic determination of anterior/posterior axis, embryo; protein stabilization; in utero embryonic development; apoptosis; Rac protein signal transduction; paraxial mesoderm morphogenesis; mesodermal cell migration; notochord morphogenesis; apical protein localization; embryonic body morphogenesis; regulation of protein localization; embryonic foregut morphogenesis; establishment and/or maintenance of actin cytoskeleton polarity; neural tube closure; embryonic heart tube development; innate immune response; vascular endothelial growth factor receptor signaling pathway; cell migration involved in gastrulation; endoderm development |
UniProt Code: | Q9Y2A7 |
NCBI GenInfo Identifier: | 12643947 |
NCBI Gene ID: | 10787 |
NCBI Accession: | Q9Y2A7.1 |
UniProt Secondary Accession: | Q9Y2A7,O60329, Q53QN5, Q53S94, Q53Y35, |
UniProt Related Accession: | Q9Y2A7 |
Molecular Weight: | 129,517 Da |
NCBI Full Name: | Nck-associated protein 1 |
NCBI Synonym Full Names: | NCK-associated protein 1 |
NCBI Official Symbol: | NCKAP1 |
NCBI Official Synonym Symbols: | HEM2; NAP1; NAP125; p125Nap1 |
NCBI Protein Information: | nck-associated protein 1; membrane-associated protein HEM-2 |
UniProt Protein Name: | Nck-associated protein 1 |
UniProt Synonym Protein Names: | Membrane-associated protein HEM-2; p125Nap1 |
Protein Family: | Nck-associated protein |
UniProt Gene Name: | NCKAP1 |
UniProt Entry Name: | NCKP1_HUMAN |