NAT2 Antibody (PACO28502)
- SKU:
- PACO28502
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NAT2 Antibody (PACO28502) |
抗体コード: | PACO28502 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Arylamine N-acetyltransferase 2 protein (1-290AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: NAT2 antibody at 6µg/ml + Mouse brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 34 kDa Observed band size: 34 kDa . |
![]() | Immunofluorescent analysis of A549 cells using PACO28502 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO28502 at dilution of 1:100. |
バックグラウンド: | Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. |
シノニム: | Arylamine N-acetyltransferase 2 (EC 2.3.1.5) (Arylamide acetylase 2) (N-acetyltransferase type 2) (NAT-2) (Polymorphic arylamine N-acetyltransferase) (PNAT), NAT2, AAC2 |
UniProt Protein Function: | NAT2: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. Belongs to the arylamine N-acetyltransferase family. |
UniProt Protein Details: | Protein type:Acetyltransferase; EC 2.3.1.5; Secondary Metabolites Metabolism - caffeine; Translation; Xenobiotic Metabolism - drug metabolism - other enzymes Chromosomal Location of Human Ortholog: 8p22 Cellular Component: cytosol Molecular Function:arylamine N-acetyltransferase activity; protein binding Biological Process: xenobiotic metabolic process Disease: Acetylation, Slow |
NCBI Summary: | This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008] |
UniProt Code: | P11245 |
NCBI GenInfo Identifier: | 114238 |
NCBI Gene ID: | 10 |
NCBI Accession: | P11245.1 |
UniProt Secondary Accession: | P11245,O43637, O60654, O60655, Q13146, Q16697, Q2MLE4 Q2MLF5, Q2MLG8, Q2MLJ6, Q2MLK4, Q2MLK6, |
UniProt Related Accession: | P11245 |
Molecular Weight: | 34kDa |
NCBI Full Name: | Arylamine N-acetyltransferase 2 |
NCBI Synonym Full Names: | N-acetyltransferase 2 |
NCBI Official Symbol: | NAT2 |
NCBI Official Synonym Symbols: | AAC2; PNAT; NAT-2 |
NCBI Protein Information: | arylamine N-acetyltransferase 2 |
UniProt Protein Name: | Arylamine N-acetyltransferase 2 |
UniProt Synonym Protein Names: | Arylamide acetylase 2; N-acetyltransferase type 2; NAT-2; Polymorphic arylamine N-acetyltransferase; PNAT |
Protein Family: | N-terminal acetyltransferase |
UniProt Gene Name: | NAT2 |