N6AMT1 Antibody (PACO13528)
- SKU:
- PACO13528
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | N6AMT1 Antibody (PACO13528) |
抗体コード: | PACO13528 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human N6AMT1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | N-6 adenine-specific DNA methyltransferase 1 (putative);N6AMT1;C21orf127;HEMK2;MGC19995;MTQ2;N6AMT;PRED28 ; |
UniProt Protein Function: | N6AMT1: Heterodimeric methyltransferase that catalyzes N5- methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid. Belongs to the eukaryotic/archaeal PrmC-related family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.1.1.-; Methyltransferase Chromosomal Location of Human Ortholog: 21q21.3 Cellular Component: protein complex Molecular Function:protein binding; nucleic acid binding; protein methyltransferase activity Biological Process: protein amino acid methylation; positive regulation of cell growth |
NCBI Summary: | This gene encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jul 2014] |
UniProt Code: | Q9Y5N5 |
NCBI GenInfo Identifier: | 313104228 |
NCBI Gene ID: | 29104 |
NCBI Accession: | Q9Y5N5.3 |
UniProt Secondary Accession: | Q9Y5N5,Q96F73, |
UniProt Related Accession: | Q9Y5N5 |
Molecular Weight: | Calculated MW: 19kDa/22kDaObserved MW: 23kDa |
NCBI Full Name: | HemK methyltransferase family member 2 |
NCBI Synonym Full Names: | N-6 adenine-specific DNA methyltransferase 1 (putative) |
NCBI Official Symbol: | N6AMT1 |
NCBI Official Synonym Symbols: | MTQ2; HEMK2; N6AMT; PRED28; C21orf127; m.HsaHemK2P |
NCBI Protein Information: | hemK methyltransferase family member 2; N6-DNA-methyltransferase; n(6)-adenine-specific DNA methyltransferase 1 |
UniProt Protein Name: | HemK methyltransferase family member 2 |
UniProt Synonym Protein Names: | M.HsaHemK2P; N(6)-adenine-specific DNA methyltransferase 1 |
Protein Family: | HemK methyltransferase family |
UniProt Gene Name: | N6AMT1 |
UniProt Entry Name: | HEMK2_HUMAN |