MYOM1 Antibody (PACO13525)
- SKU:
- PACO13525
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MYOM1 Antibody (PACO13525) |
抗体コード: | PACO13525 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human MYOM1-Specific |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | myomesin 1, 185kDa;MYOM1;MGC134946;MGC134947;SKELEMIN ; |
UniProt Protein Function: | myomesin 1: Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent. 2 isoforms of the human protein are produced by alternative splicing.Protein type: CytoskeletalChromosomal Location of Human Ortholog: 18p11.31Cellular Component: M band; striated muscle thick filamentMolecular Function: identical protein binding; protein binding; protein homodimerization activity; structural constituent of muscleBiological Process: positive regulation of defense response to virus by host |
UniProt Protein Details: | |
NCBI Summary: | The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | P52179 |
NCBI GenInfo Identifier: | 212276443 |
NCBI Gene ID: | 8736 |
NCBI Accession: | P52179.2 |
UniProt Secondary Accession: | P52179,Q14BD6, Q6H969, Q6ZUU0 |
UniProt Related Accession: | P52179 |
Molecular Weight: | 177,700 Da |
NCBI Full Name: | Myomesin-1 |
NCBI Synonym Full Names: | myomesin 1 |
NCBI Official Symbol: | MYOM1 |
NCBI Official Synonym Symbols: | SKELEMIN |
NCBI Protein Information: | myomesin-1 |
UniProt Protein Name: | Myomesin-1 |
UniProt Synonym Protein Names: | 190 kDa connectin-associated protein; 190 kDa titin-associated protein; Myomesin family member 1 |
Protein Family: | Myomesin |
UniProt Gene Name: | MYOM1 |
UniProt Entry Name: | MYOM1_HUMAN |