MYO1A Antibody (PACO10699)
- SKU:
- PACO10699
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MYO1A Antibody (PACO10699) |
抗体コード: | PACO10699 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human MYO1A |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | myosin IA;MYO1A;BBMI;DFNA48;MIHC;MYHL ; |
UniProt Protein Function: | MYO1A: Involved in directing the movement of organelles along actin filaments (Potential). Defects in MYO1A are the cause of deafness autosomal dominant type 48 (DFNA48). DFNA48 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. |
UniProt Protein Details: | Protein type:Actin-binding; Motor; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 12q13-q14 Cellular Component: basolateral plasma membrane; brush border; cortical actin cytoskeleton; cytoplasm; filamentous actin; lateral plasma membrane; microvillus Biological Process: sensory perception of sound; vesicle localization Disease: Deafness, Autosomal Dominant 48 |
NCBI Summary: | This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q9UBC5 |
NCBI GenInfo Identifier: | 13431715 |
NCBI Gene ID: | 4640 |
NCBI Accession: | Q9UBC5.1 |
UniProt Secondary Accession: | Q9UBC5,Q9UQD7, |
UniProt Related Accession: | Q9UBC5 |
Molecular Weight: | 118,401 Da |
NCBI Full Name: | Unconventional myosin-Ia |
NCBI Synonym Full Names: | myosin IA |
NCBI Official Symbol: | MYO1A |
NCBI Official Synonym Symbols: | BBMI; MIHC; MYHL; DFNA48 |
NCBI Protein Information: | unconventional myosin-Ia |
UniProt Protein Name: | Unconventional myosin-Ia |
UniProt Synonym Protein Names: | Brush border myosin I; BBM-I; BBMI; Myosin I heavy chain; MIHC |
Protein Family: | Unconventional myosin |
UniProt Gene Name: | MYO1A |
UniProt Entry Name: | MYO1A_HUMAN |