MYLK3 Antibody (PACO10695)
- SKU:
- PACO10695
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MYLK3 Antibody (PACO10695) |
抗体コード: | PACO10695 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human |
免疫原: | Human MYLK3 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | myosin light chain kinase 3;MYLK3;MGC126319;MGC126320;MLCK;MLCK2;caMLCK ; |
UniProt Protein Function: | caMLCK: Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:CAMK group; EC 2.7.11.18; Kinase, protein; MLCK family; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor) Chromosomal Location of Human Ortholog: 16q11.2 Cellular Component: actin cytoskeleton; cytoplasm; cytosol; intracellular Molecular Function:ATP binding; calmodulin-dependent protein kinase activity; myosin light chain kinase activity Biological Process: cardiac myofibril assembly; cellular response to interleukin-1; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; protein amino acid phosphorylation; regulation of vascular permeability during acute inflammatory response; sarcomere organization; sarcomerogenesis |
NCBI Summary: | Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008] |
UniProt Code: | Q32MK0 |
NCBI GenInfo Identifier: | 815930021 |
NCBI Gene ID: | 91807 |
NCBI Accession: | NP_001295230.1 |
UniProt Secondary Accession: | Q32MK0,Q96DV1, |
UniProt Related Accession: | Q32MK0 |
Molecular Weight: | 52,723 Da |
NCBI Full Name: | myosin light chain kinase 3 isoform 2 |
NCBI Synonym Full Names: | myosin light chain kinase 3 |
NCBI Official Symbol: | MYLK3 |
NCBI Official Synonym Symbols: | MLCK; MLCK2; caMLCK |
NCBI Protein Information: | myosin light chain kinase 3 |
UniProt Protein Name: | Myosin light chain kinase 3 |
UniProt Synonym Protein Names: | Cardiac-MyBP-C-associated Ca/CaM kinase; Cardiac-MLCK |
Protein Family: | Myosin light chain kinase |
UniProt Gene Name: | MYLK3 |