MTUS1 Antibody (PACO10654)
- SKU:
- PACO10654
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MTUS1 Antibody (PACO10654) |
抗体コード: | PACO10654 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human MTUS1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | mitochondrial tumor suppressor 1;MTUS1;ATIP;DKFZp586D1519;DKFZp686F20243;FLJ14295;KIAA1288;MP44;MTSG1 ; |
UniProt Protein Function: | MTUS1: Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth. Defects in MTUS1 may be a cause of hepatocellular carcinoma (HCC). Belongs to the MTUS1 family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Tumor suppressor; Mitochondrial Chromosomal Location of Human Ortholog: 8p22 Cellular Component: extracellular space |
NCBI Summary: | This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9ULD2 |
NCBI GenInfo Identifier: | 158706128 |
NCBI Gene ID: | 57509 |
NCBI Accession: | Q9ULD2.2 |
UniProt Secondary Accession: | Q9ULD2,Q63HJ6, Q659F4, Q6PK49, Q6URW7, Q8N4M6, A8K135 B2RBJ6, B3KWJ9, B4DH03, B9EGA1, D3DSP8, |
UniProt Related Accession: | Q9ULD2 |
Molecular Weight: | 48,050 Da |
NCBI Full Name: | Microtubule-associated tumor suppressor 1 |
NCBI Synonym Full Names: | microtubule associated tumor suppressor 1 |
NCBI Official Symbol: | MTUS1 |
NCBI Official Synonym Symbols: | ATBP; ATIP; ICIS; MP44; MTSG1 |
NCBI Protein Information: | microtubule-associated tumor suppressor 1 |
UniProt Protein Name: | Microtubule-associated tumor suppressor 1 |
UniProt Synonym Protein Names: | AT2 receptor-binding protein; Angiotensin-II type 2 receptor-interacting protein; Mitochondrial tumor suppressor 1 |
Protein Family: | Microtubule-associated tumor suppressor |
UniProt Gene Name: | MTUS1 |
UniProt Entry Name: | MTUS1_HUMAN |