MTRR Antibody, FITC conjugated (PACO42316)
- SKU:
- PACO42316
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | MTRR Antibody, FITC conjugated (PACO42316) |
抗体コード: | PACO42316 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Methionine synthase reductase protein (1-725AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Involved in the reductive regeneration of cob(I)alamin (vitamin B12) cofactor required for the maintenance of methionine synthase in a functional state. Necessary for utilization of methylgroups from the folate cycle, thereby affecting transgenerational epigenetic inheritance. Folate pathway donates methyl groups necessary for cellular methylation and affects different pathways such as DNA methylation, possibly explaining the transgenerational epigenetic inheritance effects. |
シノニム: | Methionine synthase reductase (MSR) (EC 1.16.1.8), MTRR |
NCBI Summary: | This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
UniProt Code: | Q9UBK8 |
NCBI GenInfo Identifier: | 169790958 |
NCBI Gene ID: | 4552 |
NCBI Accession: | NP_002445 |
UniProt Related Accession: | Q9UBK8 |
Molecular Weight: | |
NCBI Full Name: | methionine synthase reductase |
NCBI Synonym Full Names: | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
NCBI Official Symbol: | MTRR |
NCBI Official Synonym Symbols: | MSR; cblE |
NCBI Protein Information: | methionine synthase reductase |
UniProt Protein Name: | Methionine synthase reductase |
Protein Family: | Mycothione reductase |
UniProt Gene Name: | MTRR |
UniProt Entry Name: | MTRR_HUMAN |